Books : virology

The main strength of the book is the great molecular detail the author achieves, but still at a level that an undergraduate student should be able to master. I like the blend of molecular with medical; this has been lacking in most virology books that I have considered using. - Darlene Walro, Walsh University

Like other biomedical sciences, medical virology has undergone a revolution of diagnostic and scientific approaches through the advent of molecular biological techniques. Developing and maintaining an appropriate mixture of classical and molecular techniques for viral analysis is one of the challenges of medical virology today, and this volume addresses these issues. Topics covered include a broad description of classical techniques in viral diagnosis, nucleic acid detection by extraction and hybridization, use of the polymerase chain reaction, the application of various molecular techniques to aspects of the epidemiology of virus infections, and the principles and practical approaches to the analysis of viral evolution. The book will be of interest to students, researchers and professionals in medical virologoy, particularly hospital workers, microbiology, and molecular biology.

Principles of Molecular Virology, Fourth Edition provides an essential introduction to modern virology in a clear and concise manner. It is a highly enjoyable and readable text with numerous illustrations that enhance the reader's understanding of important principles. * New material on virus structure, virus evolution, zoonoses, bushmeat, SARS and bioterrorism * Standard version includes CD-ROM with FLASH animations, virtual interactive tutorials and experiments, self-assessment questions, useful online resources, along with the glossary, classification of subcellular infectious agents and history of virology

Introduction to Modern Virology has been an established student text for over 25 years. Providing an integrated account of the subject across different host systems, with an emphasis on human and animal viruses, this book covers the field of virology from molecular biology to disease processes using a unique systems approach. Featuring an all new art program in full color, the new edition has been updated throughout, and reorganized into thematic sections on the fundamental nature of viruses, their growth in cells, their interactions with the host organism and their role as agents of human disease. There is a new chapter on Human Viral Disease and rapidly developing areas, such as the use of viruses as gene therapy vectors, have been included. The 6th edition is even more accessible, now including key points and integrative questions in every chapter, as well as text boxes emphasizing take-home messages, evidence underpinning the main concepts, and further information for more advanced readers. Prevention and therapy, evolution and emerging viruses receive particular attention and specific chapters address the major infectious challenges posed by HIV, pandemic influenza and BSE. This highly accessible text provides ideal reading for all undergraduate and postgraduate students of biology and medicine wishing to study virology.

Mary K. L. Collins has assembled in Practical Molecular Virology a vanguard collection of readily repeatable methods for gene transfer and expression using a variety of recombinant viral vectors. In keeping with the established tradition of the series, each technique is presented in an easy-to-follow format designed to work for the novice as well as the seasoned expert. Chapters cover: a [ life cycles of specific retroviruses and how recombinant vectors are constructed a [ PCR techniques a [ poliovirus vectors a [ herpesvirus vectors a [ syncytial assays a [ cell lineage studies a [ baculovirus and adenovirus vectors a [ SV40 and EBV vectors a [ viruses in gene transfer to eukaryotic cells The wealth of material devoted to recombinant retroviral methods and their applications make Practical Molecular Virology and extremely timely volume, one that will find widespread use throughout biological and biomedical research.

This new Edition of A Practical Guide to Clinical Virology has been thoroughly updated and is a practical, highly illustrated, quick reference guide to clinical virology. It brings together the essentials of the subject in a entertaining and informative style, describing in turn the clinical features, the symptoms and signs of each of the viral diseases, as well as summarising the epidemiology, laboratory diagnosis and therapy in each case. This book also includes general chapters such as classification, diagnosis of infection, antiviral drugs, vaccines and different clinical syndromes. Features include: Chapter summaries for quick reference Cartoon illustrations New chapters on Human Herpes Virus 6 Hepatitis C Hepatitis E Emerging Viruses Polyoma viruses Comprehensive coverage Clear and concise format Each chapter is easy to read and well organised, ensuring that this is an invaluable textbook for all medical, biomedical, microbiology and applied biology students. In addition, it will provide an excellent reference for nurses, occupational health and infection control departments, public health and diagnostic laboratories.

Molecular Virology, Molecular and Medical Aspects of Disease-Causing Viruses in Man and Animals

Applied Virology Research: New Vaccines and Chemotherapy: Volume 1

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Following the considerable success of the first edition of Plant Virology Protocols, this exciting new edition covers the many new techniques that are now applied to the examination and understanding of plant viruses. Each section of Plant Virology Protocols, Second Edition presents the most novel methods and protocols to allow researchers more effective approaches to study plant viruses. The many subjects covered in this important new edition range from techniques for investigating viral nucleic acid sequence, protein analysis and investigation of protein function, techniques for microscopy/GFP visualization and analysis/protein tagging/generation of infectious clones and other such tools, as well as areas of genomics and interactions with host factors and plant-based studies. Plant Virology Protocols, Second Edition: From viral sequence to protein function is indispensable to laboratory investigators studying plant viruses.

Completely revised and updated to reflect important advances in the field, Principles of Virology, Second Edition continues to fill the gap between simple introductory texts and very advanced reviews of major virus families, introducing upper-level undergraduates, graduate students, and medical students to all aspects of virology. The second edition retains all of the defining and much-praised features of the first edition, focusing on concepts and principles and presenting a comprehensive treatment from molecular biology to pathogenesis and infection control. Written in an engagingly readable style and generously illustrated with over 400 full-color illustrations, this approachable volume offers detailed examples that illustrate common principles, specific strategies adopted by different viruses to ensure their reproduction, and the current state of virology research. The book is divided into chapters that focus on specific topics rather than individual viruses, and allows the student to visualize common themes that cut across virus families, emphasizing the shared features of different viruses. Drawing on the extensive teaching experience of each of its distinguished authors, Principles of Virology illustrates why and how animal viruses are studied and demonstrates, using well-studied systems, how the knowledge gained from such model viruses can be used to study viral systems about which our knowledge is still quite limited. A thorough introduction to principles of viral pathogenesis, a broad view of viral evolution, a discussion of how viruses were discovered, and how the discipline of virology came to be are also provided. A variety of special boxes high-light key experiments,background material, caveats, and much more. The text focuses on concepts and principles and covers not only aspects of molecular biology, but also pathogenesis, evolution, emergence, and control, and will also be a valuable resource for practicing physicians and scientists.

A cutting-edge collection of basic and state-of-the-art methods optimized for investigating the molecular biology of this class of retrovirus. These readily reproducible techniques range from methods for the isolation and detection of human retroviruses to cutting-edge methods for exploring the interplay between the viruses and the host. Here, the researcher will find up-to-date techniques for the isolation and propagation of HIV, HTLV, and foamy virus from a variety of sources. There are also assays for determining the cell tropism of HIV-1, the coreceptor usage of HIV-1, and human gene expression with HIV-1 infection by microarrays, as well as for phenotyping HIV-1 infected monocytes and examining their fitness. Highlights include the detection and quantification of HIV-1 in resting CD4+, a new cloning system for making recombinent virus, cDNA microarrays, and the determination of genetic polymorphisms in two recently identified HIV-1 co-factors that are critical for HIV-1 infection.

This completely rewritten, revised, and updated new edition provides an indispensable introduction to medical microbiology for students, trainee doctors and laboratory workers. Its contents cover advances in molecular microbiology especially for diagnostic techniques and include such topical subjects as MRSA, C. difficile, avian influenza and vCJD. The text is illustrated throughout with 130 illustrations most in full colour.

We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreedunderstanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impeded our efforts towards developing effective therapies and preventive vaccines. The authors describe the emerging field of theoretical immunology in this accessible andwell-written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach tounderstanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be morewidely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimization of the design of therapy and vaccines are discussed. The bookconcludes with a glance towards the future of this fascinating, and potentially highly useful, field of study.

In recent years there has been a resurgence of interest in studying infectious diseases, especially given the alarming increase in the numbers of emerging diseases now confronting medical and veterinary science. Viral Haemorrhagic Fevers describes the progress in research and our understanding of these agents against a backdrop of continuing fear these viruses engender among health care workers and the public alike. It discusses how the study of these viral agents is directly applicable to other emerging diseases, particularly in relation to how containing these outbreaks requires a high degree of collaboration between different specialists. Primarily aimed at healthcare workers, clinicians and microbiologists, this book provides a rapid overview as to the nature of these widely varying agents linked only by their propensity of causing serious human disease.

Volume 3 is devoted to the latest diagnostic technology for virus diseases, particularly molecular methodologies.

AIDS is undeniably one of the most pressing medical emergencies of our era. It is now 12 years since the discovery of HIV and in spite of a world-wide research effort no proven method for controlling AIDS has been developed. HIV Volumes 1 and 2 are guides to studying HIV in the laboratory focusing on specialized techniques unique to this field. Both books provide the novice entering HIV research with clear instructions on how to perform standard experiments as well as including many novel methods described in detail for the first time. Volume 1 describes studies of the virus and infected cells and covers techniques for handling HIV safely, for studying viral entry, replication and neutralization and basic immunological techniques.

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2006 is 3.48 placing it 7th in the highly competitive category of virology.